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Gabapentin-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of gabapentin in urine relative to creatinine, which helps account for differences in urine concentration.

Quick summary

["This test helps determine how much gabapentin your body is excreting and may be used to monitor treatment or possible toxicity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72811-3
Short code
Gabapentin/Creat Ur
Synonyms
Gabapentin/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures gabapentin, a medicine used to treat seizures and certain nerve pain, in your urine. The result is compared with the amount of creatinine in the urine so that variations in urine concentration do not fully affect interpretation.

Why might I need this test?

Your clinician may order this test to check medication exposure, investigate whether you are taking the prescribed amount, or evaluate signs of gabapentin toxicity. It may also be used during routine monitoring of gabapentin treatment.

How is the test performed?

A urine sample is tested in the laboratory to determine the amounts of gabapentin and creatinine. The laboratory then calculates the gabapentin-to-creatinine ratio. The sample may be collected as a spot urine sample or over a specified period, depending on your clinician's instructions.

How do I prepare for the test?

Collect the urine exactly as instructed, including any specified collection period. Record the time of your last gabapentin dose and the urine collection time, and tell your clinician about other medicines you take. Do not change your gabapentin dose unless your clinician directs you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher-than-expected result may reflect recent dosing, taking more than prescribed, reduced elimination, or impaired kidney function. A lower-than-expected result may indicate a missed dose, reduced intake, poor absorption, or unusually rapid elimination. Interpretation depends on the prescribed dose, timing of the sample, kidney function, and clinical symptoms.

Short name

Urine Gabapentin Ratio

Frequently asked questions

Is this the same as a standard kidney function test?
No. Creatinine is used in this test to adjust the urine gabapentin result for urine concentration, but this test is primarily used for medication monitoring rather than to diagnose kidney disease.
Does a high result mean gabapentin is dangerous?
Not necessarily. A higher result can occur when the medicine is taken recently or when the dose is higher, so your clinician will interpret it alongside the dose, collection time, kidney function, and any symptoms.
Should I stop taking gabapentin before the test?
Do not stop or change your medication without medical advice. Continue taking it as prescribed and provide the timing of your last dose so the result can be interpreted accurately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy