GABA (Gamma-Aminobutyric Acid) in Saliva

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like anxiety, insomnia, or mood swings that aren’t fully explained by other conditions. It could also be part of a broader evaluation for neurological disorders or to monitor treatment effects for conditions like epilepsy or certain psychiatric treatments.

What to Expect Before the Test

No special preparation is needed for this test. You’ll likely provide a small saliva sample, which is collected by gently pressing a collection device to your cheek for a few seconds. Avoid eating, drinking, or chewing gum for at least 30 minutes before the test.

What the Results Mean

GABA levels can vary based on diet, stress, and other factors. While reference ranges aren’t universally standardized, very low levels might suggest increased anxiety or stress responses, while higher levels could be associated with relaxation or certain medications. Always discuss your results with your provider.

Common Causes of Abnormal Results

Factors that might affect GABA levels include certain medications (like antidepressants or anticonvulsants), diet (e.g., high-protein or alcohol intake), stress, or underlying neurological conditions. Your provider will consider these when interpreting your results.