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GABA (Gamma-Aminobutyric Acid) in Serum or Plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of GABA, a natural chemical in your blood that helps regulate nerve cell activity. It may be used to assess brain function or monitor conditions affecting GABA levels.

Quick summary

["GABA helps calm brain activity; levels may be checked for neurological concerns or treatment follow-up."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
87496-6
Short code
Gabapentin SerPlBld Ql Scn
Synonyms
Gabapentin SerPlBld Ql Scn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like seizures, anxiety, or neurological issues. It could also be part of evaluating conditions such as epilepsy, brain tumors, or certain metabolic disorders. Rarely, it may be used to monitor medications that affect GABA levels.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if instructed. Avoid alcohol or certain medications that could affect results for 24 hours beforehand.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it typically doesn’t cause significant discomfort. The blood sample will be sent to a lab for analysis.

What the Results Mean

Results are compared to a general reference range, though exact values can vary by lab. Abnormally high or low levels may suggest underlying health concerns, such as neurological disorders or metabolic imbalances.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

GABA levels can be elevated in conditions like epilepsy, brain tumors, or certain genetic disorders. Low levels may indicate metabolic disorders, nerve damage, or exposure to toxins. Always discuss results with your provider for personalized interpretation.

Short name

GABA Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab and testing schedule. Follow-up with your healthcare provider to discuss findings.
Can I eat or drink before this test?
Check with your provider for specific instructions, but generally, avoid food/fast for 8–12 hours and alcohol for 24 hours before drawing blood.
Does this test require fasting?
Some labs may require fasting; confirm with your provider or lab technician before your appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy