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Serum or plasma concentration of gabapentin (substance concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of gabapentin, a medication used to treat certain types of seizures or nerve pain, in your blood.

Quick summary

["Knowing your gabapentin level helps your doctor monitor your dose and adjust it as needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
25425-0
Short code
Gabapentin SerPl-sCnc
Synonyms
Gabapentin SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking gabapentin to check if the medication is working properly, to adjust your dose, or to detect any unusual levels that might affect your health. It can also help identify if you’re experiencing side effects or if your body is processing the drug differently than expected.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast before the test, but this depends on your doctor’s instructions. Bring a list of all medications you’re taking, including gabapentin, to your appointment.

How the Test Is Done

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but the procedure is quick. The blood sample is then sent to a lab for testing.

What the Results Mean

Results are typically reported as a concentration of gabapentin in your blood. While reference ranges can vary by lab, very high or very low levels may signal issues like poor absorption, overdose, or drug interactions. Your doctor will interpret the results in the context of your medical history and symptoms.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Gabapentin Level

Frequently asked questions

What Are Common Causes of Abnormal Results?
Abnormally high levels of gabapentin may occur if you take too much of the medication, have liver or kidney problems affecting drug metabolism, or experience poor absorption. Abnormally low levels might suggest your body is eliminating the drug too quickly or you’re not taking it as prescribed. Always discuss any concerns with your doctor.
How Often Should This Test Be Done?
The frequency depends on your treatment plan. Your doctor may recommend testing during initial dose adjustments, if you’re experiencing side effects, or if you have conditions that could affect gabapentin levels (e.g., kidney disease). Follow your healthcare provider’s guidance.
Can Diet or Other Medications Affect This Test?
Yes, certain foods, supplements, or other medications (like antacids or certain antibiotics) may interact with gabapentin and influence test results. Always inform your doctor about all medications, vitamins, or herbal products you’re taking.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy