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Generalized Amino Acid Screening in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of various amino acids in your blood serum, helping identify potential imbalances that may require medical evaluation.

Quick summary

["This screening can help detect metabolic disorders or conditions affecting amino acid metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90367-4
Short code
GA Est from PE
Synonyms
GA Est from PE
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
estimated-from-physical-examination
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, muscle weakness, or unexplained weight changes, or if you have a known condition like inborn errors of metabolism.

Common Conditions Monitored

Conditions such as phenylketonuria, maple syrup urine disease, or other metabolic disorders may be monitored through this screening.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is processed to separate serum, which is then analyzed for amino acid levels.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours if instructed by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal amino acid levels can indicate underlying metabolic disorders. Elevated levels of certain amino acids may suggest conditions like liver disease or kidney problems, while low levels might point to nutritional deficiencies or genetic disorders.

Short name

Amino Acid Profile

Frequently asked questions

What Does an Abnormal Result Mean?
An abnormal result doesn’t necessarily mean you have a specific condition. It may prompt further testing or a referral to a specialist for more detailed evaluation.
Will I Need Follow-Up Tests?
Yes, if your results are abnormal, your healthcare provider may recommend additional tests or treatments to address potential metabolic issues.
Can Diet or Medication Affect This Test?
Yes, certain diets, medications, or supplements can influence amino acid levels. Always inform your provider about any medications or dietary changes you’re making.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy