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Fructosamine (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the average blood sugar levels over the past two to three weeks by tracking glycated proteins, specifically albumin, in your serum.

Quick summary

["Helps assess long-term blood sugar control in people with diabetes or prediabetes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33075-3
Short code
GA from AC.Merz 88
Synonyms
GA from AC.Merz 88
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-ac-merz
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a fructosamine test to monitor how well your blood sugar is being controlled over time, especially if you have diabetes or are at risk. Unlike hemoglobin A1c, which measures average blood sugar over roughly three months, fructosamine reflects the most recent changes in your blood sugar levels, providing a snapshot of recent metabolic stability.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The serum portion of the blood is then analyzed to measure fructosamine levels using an immunoassay method.

What Do the Results Mean?

Fructosamine results help determine whether your blood sugar management plan is effective. Higher levels may indicate poor control of blood sugar, while lower levels may suggest better regulation. However, reference ranges can vary by lab, so discuss your results with your healthcare provider.

What Are Common Causes of Abnormal Results?

Elevated fructosamine levels can be due to high blood sugar, infections, stress, or certain medications. Low levels may result from conditions that reduce protein synthesis or severe malnutrition. Always review results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fructosamine Level

Frequently asked questions

How often should I get this test?
Your healthcare provider will determine the frequency based on your diabetes management needs. Typically, fructosamine tests are done every few months to monitor trends in blood sugar control.
What does a normal range mean for me?
A normal range is not absolute—it depends on your lab and overall health. Your results will be interpreted in relation to your specific needs, blood sugar history, and treatment goals.
Can lifestyle changes affect fructosamine levels?
Yes, diet, exercise, and medication adherence can influence fructosamine levels. Small, consistent lifestyle changes often lead to improved glycemic control over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy