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Bromocresol Purple Protein Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution across different fractions in your blood serum or plasma using bromocresol purple dye binding. It helps identify abnormal protein patterns, such as those seen in conditions like multiple myeloma or severe liver disease.

Quick summary

["This test helps doctors check for unusual protein levels that may signal hidden health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11897-6
Short code
GA from BPC
Synonyms
GA from BPC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-bpc
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The bromocresol purple dye binds to proteins of varying sizes, creating distinct bands when separated by electrophoresis. Each band represents a group of proteins with similar molecular weights. The test evaluates the relative amounts of these protein groups, including albumin and globulins.

Common Conditions Evaluated

This test is often used to diagnose or monitor conditions affecting protein synthesis, storage, or breakdown. It may be part of a broader evaluation for conditions like multiple myeloma, amyloidosis, or chronic liver disease.

How the Test Works

A small blood sample is drawn and processed into serum or plasma. The sample is then exposed to bromocresol purple dye, which reacts differently with proteins of varying sizes. An electric field separates the proteins, creating visible bands that indicate protein concentration levels.

Why It Matters

Abnormal protein patterns can signal underlying health problems, such as protein loss, overproduction of specific proteins, or dysfunction in organs like the liver or kidneys. Early detection can guide treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test provides critical information for diagnosing and managing conditions that alter protein metabolism, such as plasma cell disorders, liver disease, or systemic protein abnormalities. It helps clinicians assess the severity and progression of these conditions.

Short name

BCP Protein Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if they suspect conditions like multiple myeloma, amyloidosis, or severe liver disease. It can also be used to monitor protein levels in chronic illnesses or after treatments that affect protein production.
What does it mean if my results are abnormal?
Abnormal results may indicate an excess or deficiency of certain proteins, which could point to conditions like multiple myeloma (where abnormal proteins accumulate), liver disease (where protein synthesis is impaired), or other metabolic disorders. Your doctor will interpret results in the context of your overall health.
How often should I get this test?
The frequency depends on your health status and treatment plan. If you have a chronic condition, your doctor may schedule follow-up tests periodically to monitor protein levels and treatment effectiveness.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy