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Serum Creatinine (Creatinine)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function.

Quick summary

["Your kidneys filter waste from blood; this test checks how well they’re doing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11906-5
Short code
GA from BPD.Kurtz80
Synonyms
GA from BPD.Kurtz80
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-bpd-kurtz
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine levels can indicate how well your kidneys are working. High levels may signal kidney damage or disease, while low levels could suggest dehydration or muscle loss. Your doctor may order this test to monitor kidney health, especially if you have conditions like diabetes, high blood pressure, or a history of kidney problems.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Drink plenty of water the day before to help your kidneys function normally. Avoid heavy exercise or strenuous activity that could raise muscle breakdown and creatinine levels temporarily.

What Happens During the Test

A healthcare provider will draw blood from a vein in your arm. The sample is sent to a lab for analysis. The test typically takes a few minutes, and you may feel slight discomfort or bruising at the injection site.

What the Results Mean

Results are compared to a reference range specific to your age, sex, and overall health. Abnormal results may prompt further testing or follow-up to investigate potential kidney issues. Your doctor will discuss the results with you in detail.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated creatinine levels often signal impaired kidney function, as the kidneys normally filter waste products like creatinine from the blood. Chronic kidney disease, dehydration, or conditions like heart failure can raise creatinine. Conversely, very low levels may indicate dehydration, severe muscle wasting, or liver disease. Regular monitoring of creatinine is vital for managing chronic conditions like diabetes or hypertension.

Short name

Creatinine

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status, medical history, and any conditions they’re monitoring. For example, people with diabetes or kidney disease may need it more frequently than others.
Can diet affect my creatinine levels?
Dietary protein intake can influence creatinine levels, but the effect is usually small. High-protein diets may temporarily raise creatinine, while very low-protein diets might lower it. Your doctor or dietitian can help clarify if diet changes are needed for your specific situation.
What if my results are out of the normal range?
If your results are outside the normal range, your doctor will review them with you and may order additional tests or recommend lifestyle changes. They’ll also check for underlying causes, such as kidney disease, dehydration, or other health conditions that could affect your creatinine levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy