Skip to content

Serum Creatinine (Creatinine)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function and overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33092-8
Short code
GA from CRL.Jeanty82
Synonyms
GA from CRL.Jeanty82
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-crl-jeanty
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Creatinine is a byproduct of muscle metabolism that your kidneys filter from your blood. High levels may indicate poor kidney function, while low levels could suggest dehydration or muscle loss. This test is often used alongside other kidney function tests to evaluate kidney health.

Why Might You Need This Test?

Doctors order creatinine tests to monitor kidney function, especially in people with conditions like diabetes, high blood pressure, or a history of kidney disease. It may also be used before surgeries, during pregnancy, or if you have symptoms like swelling, fatigue, or changes in urine output.

How Is This Test Done?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure creatinine levels. No special preparation is needed, but you may be asked to stop certain medications or avoid certain foods for a short time if instructed by your healthcare provider.

What Are Common Results?

Results are typically reported in milligrams per deciliter (mg/dL) or micromoles per liter (µmol/L). While exact reference ranges can vary by lab, higher-than-normal levels may signal kidney problems, while very low levels might indicate dehydration or muscle wasting. Your doctor will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition. Healthy adults may not need regular testing unless recommended by a doctor. People with kidney disease, diabetes, or high blood pressure may need it more often, such as every 3–12 months, to monitor kidney function and adjust treatments as needed.
Can diet affect my creatinine levels?
Yes, diet can influence creatinine levels. High-protein foods may temporarily increase creatinine, but your kidneys usually clear it over time. Avoiding excessive protein intake for a few days before testing may help stabilize results. Always follow your doctor’s advice for any dietary restrictions.
What if my results are abnormal?
If your creatinine levels are higher than expected, your doctor may investigate further to check for kidney issues. If levels are very low, they might look for causes like dehydration, muscle loss, or certain medications. Your doctor will discuss next steps based on your specific results and health history.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy