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Fibrinogen (Serum or Plasma) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps form clots to stop bleeding. It’s often checked when you have bleeding disorders, clotting issues, or certain medical conditions.

Quick summary

["Fibrinogen helps control bleeding and supports blood clotting—low levels may indicate bleeding risks, while high levels could signal inflammation or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33097-7
Short code
GA from Fib Length.Jeanty83
Synonyms
GA from Fib Length.Jeanty83
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-fibula-length-jeanty
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like excessive bleeding (e.g., easy bruising, nosebleeds, or heavy menstrual periods), unexplained clots, or conditions like liver disease, kidney problems, or certain cancers. It’s also used to monitor treatments for bleeding disorders or clotting problems.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your blood is drawn early in the morning. Wear a loose shirt for easy access to your arm.

What Happens During the Test

A healthcare provider will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but it’s quick and over in minutes. The blood is then sent to a lab for analysis.

What the Results Mean

Results are typically reported as a concentration (e.g., grams per liter). Low fibrinogen levels may suggest bleeding disorders or liver/kidney issues, while very high levels could indicate inflammation or other conditions. Your doctor will interpret results in the context of your health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen is crucial for blood clotting. Low levels can lead to bleeding disorders (e.g., hemophilia or von Willebrand disease) or complications after surgery. High levels may signal acute inflammation (e.g., infections, trauma) or chronic conditions like rheumatoid arthritis. Monitoring fibrinogen helps guide treatment for bleeding risks or clotting disorders.

Short name

Fibrinogen

Frequently asked questions

What causes low fibrinogen?
Low fibrinogen can result from liver disease (which affects protein production), severe infections, blood loss, or certain medications (e.g., anticoagulants). It may also appear in conditions like DIC (disseminated intravascular coagulation) or after major surgery.
What does it mean if my fibrinogen is high?
Elevated fibrinogen often points to inflammation, infection, or trauma. It can also be seen in chronic conditions like rheumatoid arthritis or certain cancers. Your doctor may investigate further if results are consistently high.
Do I need to avoid certain foods before this test?
No special diet is required, but if your doctor specified fasting, follow their instructions. Avoiding alcohol or certain medications (like blood thinners) may also be advised if they could affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy