Skip to content

Serum or plasma concentration of free fatty acids (FFAs) measured by a chemiluminescent immunoassay (CLIA)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of free fatty acids, which are a type of fat found in your blood. They play a key role in energy production and cell function.

Quick summary

["Free fatty acids help your body use energy efficiently and support normal metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33100-9
Short code
GA from FL.lessoway98
Synonyms
GA from FL.lessoway98
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-fl-lessoway
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal fat metabolism, such as high triglycerides, diabetes, or thyroid disorders. It can also help monitor certain treatments or underlying health conditions that affect fat levels in your blood.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves a blood draw, but this depends on your specific order. Always follow your provider’s instructions.

How the Test Is Performed

A small sample of blood is drawn from a vein in your arm using a needle. The blood is then processed to separate serum or plasma for testing. The lab uses a sensitive immunoassay method to detect free fatty acids.

What the Results Mean

Results are reported as a concentration value (e.g., in mmol/L or mg/dL), but exact reference ranges vary by lab. High or low levels may signal metabolic issues or other health concerns that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated free fatty acids can be associated with metabolic syndrome, insulin resistance, or conditions like pancreatitis. Low levels may indicate malabsorption, liver disease, or certain medications. Your provider will interpret results in the context of your overall health and symptoms.

Short name

Free Fatty Acids (Serum/Plasma)

Frequently asked questions

What causes free fatty acids to be tested?
Testing is often done to assess metabolic health, diagnose conditions like diabetes or thyroid disorders, or monitor treatments affecting fat metabolism.
Do I need to fast before this test?
Check with your provider—some tests require fasting, while others do not. Fasting instructions are usually provided if applicable.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab and insurance. Follow-up with your provider to discuss findings.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy