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Serum or plasma free fatty acid concentration (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of free fatty acids in your blood, which are important for energy production and fat metabolism.

Quick summary

["Free fatty acids help your body use fat for fuel and maintain energy levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33109-0
Short code
GA from HC.ASUM00
Synonyms
GA from HC.ASUM00
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-hc-asum
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may request this test to evaluate conditions affecting fat metabolism, such as diabetes, thyroid disorders, or liver/kidney disease. It can also help monitor treatment responses or diagnose metabolic syndromes.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your provider specifies it. Bring your lab results and any medications you’re taking to your appointment.

How the Test Works

A blood sample is taken from a vein in your arm. The lab then measures the concentration of free fatty acids using a sensitive chemical method, often an immunoassay or enzymatic technique.

What the Results Mean

Results are compared to a general reference range for healthy adults, but individual ranges may vary based on age, sex, and health status. High or low levels may signal underlying issues requiring further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

FFA (Free Fatty Acids)

Frequently asked questions

What could high or low FFA levels indicate?
Elevated levels may suggest conditions like uncontrolled diabetes, hyperlipidemia, or severe dehydration. Low levels could indicate malnutrition, liver disease, or certain hormonal imbalances. Always discuss results with your provider for personalized interpretation.
How often should I get this test?
Your provider will determine frequency based on your health needs. Routine checks may occur if you have metabolic disorders, chronic illnesses, or are undergoing treatments affecting fat metabolism.
Can diet or exercise affect FFA levels?
Yes—dietary fats, fasting, and physical activity can influence FFA levels. Avoiding heavy meals before testing and staying hydrated may improve accuracy. Ask your provider for personalized advice.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy