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Serum or plasma free fatty acid concentration (qualitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of free fatty acids in your blood, which are important energy sources for your body. Free fatty acids can rise when your body breaks down stored fat.

Quick summary

["A screening test for abnormal fat metabolism that may signal conditions like diabetes or thyroid issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33544-8
Short code
GA from OFD.Hansmann85
Synonyms
GA from OFD.Hansmann85
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-ofd-hansmann
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained weight changes, fatigue, or signs of metabolic disorders. It could also be part of routine monitoring for conditions affecting fat metabolism or energy balance.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your lab uses a fasting protocol. Wear loose clothing and fasten your shirt for easy access.

During the Test

A healthcare professional will insert a small needle into a vein in your arm to collect blood. You may feel a brief pinch, but the process usually takes just a few minutes. You can sit or lie down comfortably during the procedure.

After the Test

You’ll likely feel minor bruising or soreness at the injection site, which may last a day or two. Apply gentle pressure to the area to help reduce discomfort. Avoid heavy lifting or strenuous activity for 24 hours.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated free fatty acids may indicate conditions like uncontrolled diabetes, thyroid dysfunction, or liver/kidney problems. Low levels could suggest malabsorption, malnutrition, or certain medications. Results should be interpreted by your provider in the context of your overall health.

Short name

FFA Screen (Serum/Plasma)

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result doesn’t mean you have a specific condition—it signals that your body’s fat metabolism may be disrupted. Your provider will discuss next steps, such as lifestyle changes, dietary adjustments, or further testing.
How often will I need this test?
Frequency depends on your health status. If you have a known condition (e.g., diabetes), your provider may order this test annually or as needed. If it’s a one-time screening, they’ll let you know when follow-up is needed.
Can I eat or drink before this test?
Check with your provider first, as fasting may be required for accuracy. If fasting isn’t required, you can eat and drink normally, but avoid alcohol for 24 hours before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy