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Serum or plasma concentration of free fatty acids (specifically long-chain fatty acids, measured via enzymatic method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of certain long-chain fatty acids in your blood, which can help assess fat metabolism and energy production.

Quick summary

["Understanding your fatty acid balance may support overall metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33132-2
Short code
GA from TCD.Chitty94
Synonyms
GA from TCD.Chitty94
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-tcd-chitty
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions related to abnormal fat metabolism, such as unexplained weight changes, metabolic syndrome, or suspected fatty acid disorders. It may also be used in monitoring certain metabolic or endocrine conditions.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for 8–12 hours before the blood draw if your test involves fasting samples. Avoid excessive alcohol or strenuous activity 24 hours prior.

How the Test Works

A blood sample is taken from a vein in your arm. The lab then uses an enzymatic method to measure the concentration of specific long-chain fatty acids in your serum or plasma.

What the Results Mean

Results provide a quantitative profile of free fatty acids, helping identify imbalances that may relate to conditions like mitochondrial disorders, lipid metabolism issues, or other metabolic dysfunctions. Interpretation depends on clinical context and your provider’s guidance.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Free fatty acid profile

Frequently asked questions

What could cause elevated or low levels of these fatty acids?
Elevated levels may suggest conditions like diabetes, thyroid disorders, or certain genetic metabolic syndromes. Low levels could indicate malnutrition, liver disease, or impaired fat absorption. Always discuss results with your healthcare provider, as they’ll consider your full medical picture.
How often should I get this test?
This test is usually ordered as needed for specific symptoms or diagnostic purposes. Your provider will determine how often it’s repeated based on your condition and treatment plan.
Can lifestyle changes affect these results?
Yes, diet, exercise, and certain medications (like statins or thyroid hormones) can influence fatty acid levels. If you’re making changes, discuss them with your provider before retesting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy