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Fibrinogen (Serum) – Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the amount of fibrinogen, a protein that plays a key role in blood clotting. Low levels may increase your risk of bleeding, while high levels could suggest conditions like inflammation or liver disease.

Quick summary

["Fibrinogen helps control bleeding and forms clots; abnormal levels may signal health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11941-2
Short code
GA from tib len.Jeanty84
Synonyms
GA from tib len.Jeanty84
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-estimated-from-tibia-length-jeanty
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a fibrinogen test to diagnose or monitor conditions affecting blood clotting, such as bleeding disorders, liver disease, or inflammatory conditions. It can also help assess risks before surgery or during pregnancy.

What to Expect Before the Test

No special preparation is needed, but avoid eating or drinking for at least 8–12 hours before the test if instructed. Fasted results may be more accurate for some tests, but fibrinogen is typically measured on non-fasted blood.

A blood sample is drawn from a vein, usually in your arm, by a healthcare professional. The blood is sent to a lab for analysis.

The test measures fibrinogen levels in your serum (liquid part of blood after clotting). Results are reported in grams per liter (g/L).

Interpretation depends on your health status and medical history. Low fibrinogen may indicate bleeding disorders or liver disease, while very high levels could suggest inflammation or other conditions.

Normal values vary by lab, but typical ranges are often between 2.0–4.0 g/L. Your doctor will compare your result to your specific needs.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen is essential for clot formation. Low levels may increase bleeding risk, especially during surgery or trauma, while high levels can signal chronic inflammation or liver dysfunction. Doctors use these results to guide treatment for bleeding disorders, clotting disorders, or inflammatory diseases.

Short name

Fibrinogen

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can result from liver disease (e.g., cirrhosis), severe infections, blood loss, or certain medications. It may also occur in conditions like disseminated intravascular coagulation (DIC).
What causes high fibrinogen levels?
High fibrinogen is often linked to chronic inflammation (e.g., rheumatoid arthritis), infections, or malignancies. Rarely, it may be genetic or related to pregnancy.
Can diet affect fibrinogen levels?
Dietary factors like high saturated fat intake may influence inflammation, which could indirectly affect fibrinogen. However, fibrinogen is primarily measured in blood, and diet changes alone won’t alter test results unless linked to underlying conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy