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Galactitol-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of galactitol relative to creatinine in urine. It can help evaluate how the body handles galactose when galactosemia is suspected.

Quick summary

["An elevated urine galactitol-to-creatinine ratio may suggest impaired galactose metabolism but requires clinical confirmation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47857-8
Short code
Galactitol/Creat Ur-sRto
Synonyms
Galactitol/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This urine test measures galactitol, a sugar formed when galactose is metabolized, relative to creatinine. Creatinine is used to account for differences in urine concentration.

Why might I need this test?

The test may be used to evaluate suspected galactosemia, a group of inherited conditions that interfere with the body's ability to process galactose. It is usually interpreted with other laboratory, genetic, or clinical findings.

How is the test performed?

A urine sample is analyzed to determine the relative amounts of galactitol and creatinine. The laboratory may use a spot sample or a timed collection, depending on the test ordered.

How do I prepare for the test?

Follow the collection instructions provided by your clinician or laboratory. A clean-catch urine sample is usually requested, and you may be asked to collect urine for a specific period. Tell the care team about any recent changes in galactose-containing foods, such as dairy products.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine galactitol/creatinine ratio

Frequently asked questions

What does an elevated urine galactitol-to-creatinine ratio mean?
It may suggest that the body is not breaking down galactose normally, as can occur in galactosemia. The result is not diagnostic by itself and must be considered with other tests and clinical findings.
Why is creatinine included in this urine test?
Creatinine helps normalize the galactitol measurement because urine can vary greatly in concentration. This makes results easier to compare between samples.
Is fasting required before this test?
Fasting is not universally required, but instructions can vary by laboratory and clinical situation. Follow the specific preparation and collection directions provided by your healthcare professional.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy