Galactomannan in Cerebrospinal Fluid (CSF) by Chemiluminescent Immunoassay (CLIA)
This test measures a specific fungal biomarker in your spinal fluid to help detect certain infections caused by fungi like *Aspergillus*. It’s often used in high-risk patients or when other tests are inconclusive.
["A fungal infection in your brain or spinal cord may be detected early with this test."]
Key facts at a glance
- LOINC
- 108210-6
- Short code
- Galactomannan Ag CSF Ql IA
- Synonyms
- Galactomannan Ag CSF Ql IA
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 86038
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like headaches, fever, confusion, or neurological issues that could suggest a fungal infection. It’s especially useful for people with weakened immune systems, recent organ transplants, or prolonged use of broad-spectrum antibiotics.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your back to collect spinal fluid. The procedure is quick but may cause mild discomfort. You’ll lie on your side with your knees bent, and the doctor will insert a needle into your lower spine.
How the Test Works
The collected spinal fluid is tested for galactomannan, a sugar component found in fungal cell walls. The test uses a sensitive immunoassay to detect even small amounts of this biomarker, helping doctors identify fungal infections that might not show up on other tests.
Possible Results and Next Steps
A positive result strongly suggests a fungal infection, while a negative result means no detectable fungal biomarker was found. Your doctor will discuss the results with you and may recommend further testing or treatment based on your symptoms and overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Galactomannan in CSF is a key diagnostic tool for fungal meningitis or meningoencephalitis, particularly caused by *Aspergillus* species. Early detection can guide prompt treatment with antifungal medications, improving outcomes. It’s particularly valuable in patients with immune deficiencies or those who’ve received immunosuppressive therapy.
Short name
Galactomannan CSF
Frequently asked questions
What does a positive result mean?
Can this test be done on other fluids besides CSF?
Are there any side effects from the spinal tap procedure?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy