Skip to content

Serum Galectin-3 (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the protein galectin-3 in your blood, which plays a role in inflammation and fibrosis (scarring of tissues).

Quick summary

["Galectin-3 helps assess inflammation and organ scarring, often used in heart, lung, or liver conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
83099-2
Short code
Galectin 3 SerPl IA-mCnc
Synonyms
Galectin 3 SerPl IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate inflammation or tissue damage in conditions like heart failure, liver disease, or lung disorders. It can also help monitor progression or response to treatment in these conditions.

What Does a Result Mean?

Higher than expected levels may suggest ongoing inflammation or fibrosis. Lower levels might indicate reduced inflammation. However, results are interpreted in the context of your overall health and medical history.

Common Conditions Monitored

This test is often used to monitor heart failure, liver cirrhosis, pulmonary fibrosis, and other inflammatory or fibrotic diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis. Serum (liquid part of blood after clotting) is used for this test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Galectin-3 is a biomarker linked to fibrosis and inflammation. Elevated levels may indicate tissue scarring or chronic inflammation, guiding treatment decisions for conditions like heart failure, liver disease, or lung disorders. It’s not a standalone diagnosis but often used alongside other tests for a full picture.

Short name

Galectin-3

Frequently asked questions

What causes elevated galectin-3 levels?
Elevated galectin-3 levels can be due to chronic inflammation, organ scarring (fibrosis), or certain diseases like heart failure, liver disease, or lung disorders. It may also appear in conditions with ongoing tissue damage.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will discuss the results with you.
Can galectin-3 levels change with diet or exercise?
While diet and exercise can influence inflammation, galectin-3 levels are primarily tied to underlying health conditions like fibrosis or chronic inflammation. Your provider will consider lifestyle factors alongside test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy