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Serum Protein Electrophoresis (Quantitative)

Published: August 9, 2026Updated: August 17, 2026

This test measures the distribution of different protein types in your blood, often used to identify conditions affecting protein levels or patterns.

Quick summary

["Understanding your protein profile can help diagnose or monitor conditions like infections, kidney disease, or immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
72580-4
Short code
Gamma glob 24h MFr.DF Ur Elph
Synonyms
Gamma glob 24h MFr.DF Ur Elph
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
7.35
Ref high
7.45
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins into fractions based on size and electrical charge. The test quantifies the concentration of each fraction, including albumin, globulins (such as immunoglobulins), and other proteins. This helps identify imbalances that may signal underlying health issues.

Common Uses

This test is commonly used to screen for conditions like multiple myeloma, chronic liver disease, or immune system disorders. It may also be part of a broader evaluation for unexplained symptoms like fatigue, swelling, or recurrent infections.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The serum (liquid part after clotting) is then analyzed to determine protein distribution. No special preparation is needed, but fasting may be advised depending on the clinical context.

What It Can Tell You

Abnormal patterns may reveal high or low levels of specific proteins. For example, elevated globulins might suggest an immune disorder, while abnormal albumin levels could indicate liver or kidney problems. Results are interpreted by a healthcare provider based on your overall health and symptoms.

Reference range

NCBI: pH 7.35-7.45N/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, frequent infections, swelling, fatigue, or if they suspect conditions like multiple myeloma, liver disease, or immune disorders. It can also help monitor treatment progress for certain conditions.
What does an abnormal result mean?
An abnormal result doesn’t diagnose a specific condition alone but may indicate a need for further testing. For example, a shift in protein bands could signal a systemic issue requiring additional evaluation by a healthcare provider.
How long will I need to wait for results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy