Serum Protein Electrophoresis (24-Hour Fractionation Profile)

This test measures specific substances, cells, or markers found in a sample taken from your body, giving your healthcare provider important information about how well certain organs and body systems are working.

The test evaluates the concentration of various protein groups in your blood, including albumin, globulins (such as immunoglobulins), and other proteins. Electrophoresis separates these proteins based on size and charge, allowing for detailed analysis of their distribution.

Your provider may order this test to help diagnose a medical condition, monitor an ongoing health problem, check how well a treatment is working, or screen for disease even before you notice any symptoms.

Your healthcare provider may order this test to diagnose or monitor conditions like chronic kidney disease, liver disease, multiple myeloma, or other immune system disorders. It can also help assess protein malnutrition or detect unusual protein patterns that may require further investigation.

A trained professional will collect your sample, usually a small amount of blood or urine, using clean, sterile equipment. Following the preparation instructions your care team gives you helps ensure the sample is accurate and reliable.

A blood sample is drawn from a vein, typically in your arm. The serum (liquid part of blood after clotting) is then analyzed using electrophoresis to separate proteins and measure their concentrations.

Some tests require fasting or avoiding certain foods, drinks, or medications for a set period before collection. Schedule your visit according to the timing your provider recommends, and tell the staff about any medicines or supplements you take.

No special preparation is needed, but fasting is not required. Results may take several days to process, depending on laboratory workflows.