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###1: Gamma globulin [Mass/Time] in 24-Hour Urine by Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

###3: This test measures the amount of gamma globulin proteins excreted in urine over a 24-hour period. Electrophoresis separates these proteins to help evaluate unusual protein production or loss.

Quick summary

["###4: The results can help identify increased urinary protein production, including some patterns associated with monoclonal gammopathy, when interpreted with other clinical and laboratory findings."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94715-0
Short code
Gamma glob 24h Ur Elph-mRate
Synonyms
Gamma glob 24h Ur Elph-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

###5: What This Test Measures - This test measures the amount of specific substances your kidneys remove from your blood over a full 24-hour period, giving your care team a clear picture of how well your kidneys and metabolism are working.

###6: Gamma globulins are a broad group of antibodies and related proteins. This test estimates how much gamma globulin leaves the body through the urine over 24 hours and characterizes the protein pattern by electrophoresis.

###7: Why a 24-Hour Urine Collection Is Used - Your doctor may ask for a 24-hour urine collection because hormone and mineral levels change throughout the day, and collecting every sample for a full day gives a more accurate measurement than a single sample.

###8: A 24-hour collection captures all urine produced during a complete day, which can provide a more representative measurement than a single urine specimen. The collection time and any missed samples should be reported to the testing laboratory.

###9: The collected urine is analyzed using electrophoresis to separate proteins according to their electrical properties. The laboratory then reports the amount and pattern of gamma globulin present.

###10: Factors That May Affect Results - Certain medicines, vitamins, foods, intense exercise, fever, dehydration, and missing even one urine sample during the 24 hours can all change your results, so follow the collection instructions carefully.

###11: Incomplete collections, very high urine output, recent infection or vaccination, inflammation, and kidney disease can influence the measured amount. Testing should be interpreted using the laboratory's method and the clinical context.

###12: Understanding the Results - Your results are compared with a normal reference range, and values that are too high or too low may point to kidney problems, hormone imbalances, or dietary issues, but only your doctor can interpret what they mean for you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

###13: The amount of urinary gamma globulin depends on antibody production, kidney filtering, and other causes of protein loss. An increased or abnormal pattern may occur with monoclonal plasma-cell disorders, immune activation, or impaired kidney function, while low levels may reflect reduced antibody production or substantial urinary protein loss. Results should be interpreted by a healthcare professional alongside kidney function tests, serum protein studies, and other findings.

Short name

###2: 24-Hour Urine Gamma Globulin by Electrophoresis

Frequently asked questions

###14: What is gamma globulin?
###15: Gamma globulin is the blood-protein fraction that contains most antibodies. Small amounts can normally appear in urine, but increased or altered urinary patterns may have clinical significance.
###16: Why is electrophoresis used?
###17: Electrophoresis separates urinary proteins into fractions and can reveal an abnormal distribution or a concentrated band suggestive of monoclonal protein production. It does not by itself establish a specific diagnosis.
###18: What if urine is missed during the collection?
###19: An incomplete 24-hour collection can make the reported amount inaccurate, usually resulting in a falsely low value. Tell the healthcare provider whether any urine was missed; repeat testing may be needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy