###1: Gamma globulin [Mass/Time] in 24-Hour Urine by Electrophoresis
###3: This test measures the amount of gamma globulin proteins excreted in urine over a 24-hour period. Electrophoresis separates these proteins to help evaluate unusual protein production or loss.
["###4: The results can help identify increased urinary protein production, including some patterns associated with monoclonal gammopathy, when interpreted with other clinical and laboratory findings."]
Key facts at a glance
- LOINC
- 94715-0
- Short code
- Gamma glob 24h Ur Elph-mRate
- Synonyms
- Gamma glob 24h Ur Elph-mRate
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
###5: What This Test Measures - This test measures the amount of specific substances your kidneys remove from your blood over a full 24-hour period, giving your care team a clear picture of how well your kidneys and metabolism are working.
###6: Gamma globulins are a broad group of antibodies and related proteins. This test estimates how much gamma globulin leaves the body through the urine over 24 hours and characterizes the protein pattern by electrophoresis.
###7: Why a 24-Hour Urine Collection Is Used - Your doctor may ask for a 24-hour urine collection because hormone and mineral levels change throughout the day, and collecting every sample for a full day gives a more accurate measurement than a single sample.
###8: A 24-hour collection captures all urine produced during a complete day, which can provide a more representative measurement than a single urine specimen. The collection time and any missed samples should be reported to the testing laboratory.
###9: The collected urine is analyzed using electrophoresis to separate proteins according to their electrical properties. The laboratory then reports the amount and pattern of gamma globulin present.
###10: Factors That May Affect Results - Certain medicines, vitamins, foods, intense exercise, fever, dehydration, and missing even one urine sample during the 24 hours can all change your results, so follow the collection instructions carefully.
###11: Incomplete collections, very high urine output, recent infection or vaccination, inflammation, and kidney disease can influence the measured amount. Testing should be interpreted using the laboratory's method and the clinical context.
###12: Understanding the Results - Your results are compared with a normal reference range, and values that are too high or too low may point to kidney problems, hormone imbalances, or dietary issues, but only your doctor can interpret what they mean for you.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
###13: The amount of urinary gamma globulin depends on antibody production, kidney filtering, and other causes of protein loss. An increased or abnormal pattern may occur with monoclonal plasma-cell disorders, immune activation, or impaired kidney function, while low levels may reflect reduced antibody production or substantial urinary protein loss. Results should be interpreted by a healthcare professional alongside kidney function tests, serum protein studies, and other findings.
Short name
###2: 24-Hour Urine Gamma Globulin by Electrophoresis
Frequently asked questions
###14: What is gamma globulin?
###16: Why is electrophoresis used?
###18: What if urine is missed during the collection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy