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24-Hour Urinary Immunoglobulin G (IgG) Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how much Immunoglobulin G (IgG), a type of antibody in your blood, appears in your urine over a 24-hour period. It helps assess kidney function and detect conditions like IgA nephropathy or other immune-related kidney diseases.

Quick summary

["This test helps evaluate kidney health and immune system antibody excretion."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9831-9
Short code
Gamma glob 24h Ur-mRate
Synonyms
Gamma glob 24h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like persistent kidney problems, unexplained protein in urine, or a history of immune system disorders. It can also be used to monitor kidney function in certain chronic conditions.

What to Expect Before the Test

No special preparation is needed. You’ll provide a 24-hour urine collection in a sterile container. Follow your doctor’s instructions carefully to ensure accurate results, such as collecting all urine over 24 hours and discarding the first morning urine.

What the Test Involves

You’ll start and end the urine collection at the same time each day. Store the urine in a cool place until you return it to the lab. The lab will analyze the urine sample to measure IgG levels over the full period.

What the Results Mean

Results are typically reported as the amount of IgG excreted per day. Elevated levels may indicate kidney issues or immune disorders, while normal levels suggest healthy excretion. Your doctor will interpret results in relation to your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Urine Rate

Frequently asked questions

What does a high or low result mean?
High IgG excretion in urine can signal conditions like IgA nephropathy, where the immune system attacks kidney tissue. It may also appear in other kidney diseases or certain immune disorders. Low levels are less commonly significant but could indicate reduced antibody production or kidney dysfunction.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. This test may be part of routine monitoring for kidney disease, immune disorders, or other conditions requiring long-term tracking.
Can I take medications before this test?
Some medications may affect urine composition. Always inform your doctor or lab technician about all medications, supplements, or treatments you’re taking to avoid interference with test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy