Serum Protein Electrophoresis (Qualitative)
This test measures the distribution of different protein types in your blood serum using electrophoresis, a method that separates proteins based on size and charge.
["Electrophoresis helps identify abnormal protein patterns that may signal conditions like infections, immune disorders, or liver/kidney disease."]
Key facts at a glance
- LOINC
- 72583-8
- Short code
- Gamma glob MFr.DF CSF Elph
- Synonyms
- Gamma glob MFr.DF CSF Elph
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 7.35
- Ref high
- 7.45
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Proteins Does This Test Measure?
Electrophoresis splits blood proteins into five main zones: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and immunoglobulins (gamma globulins). Each zone contains proteins with distinct roles, such as transporting nutrients, fighting infections, or maintaining blood pressure.
Why Might You Need This Test?
Your doctor may order this test to investigate symptoms like fatigue, swelling, frequent infections, or unexplained weight changes. It’s also used to monitor conditions like multiple myeloma, liver disease, or autoimmune disorders.
How Is the Sample Collected?
A blood sample is drawn from a vein in your arm. The serum (liquid part of blood without clotting factors) is then separated and analyzed in a lab.
What Are Common Findings?
Abnormal patterns may show elevated or low levels of specific proteins. For example, high gamma globulins could indicate immune system issues, while low albumin might suggest liver or kidney problems.
Reference range
NCBI: pH 7.35-7.45N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for diagnosing and managing conditions affecting protein metabolism, immune function, or organ health. It helps identify subtle imbalances that standard blood tests might miss.
Frequently asked questions
What does an abnormal electrophoresis result mean?
How long does it take to get results?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy