Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using gel electrophoresis, a method that separates proteins based on size and charge. It helps identify abnormalities in protein distribution, which can indicate conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors diagnose and monitor conditions affecting protein levels in your blood."]
Key facts at a glance
- LOINC
- 13995-6
- Short code
- Gamma glob MFr Ur Elph
- Synonyms
- Gamma glob MFr Ur Elph
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 7.35
- Ref high
- 7.45
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates blood proteins into distinct bands based on their electrical charge and molecular weight. The test identifies key protein fractions, including albumin, globulins (such as immunoglobulins), and other components like fibrinogen. These bands provide insight into overall protein balance and potential abnormalities.
Why Is This Test Performed?
Doctors may order this test to investigate symptoms like fatigue, unexplained weight loss, or signs of organ dysfunction. It’s also used to monitor conditions like chronic kidney disease, liver disease, or autoimmune disorders where protein levels or patterns may change.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The serum (liquid part after clotting) is then prepared for electrophoresis. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.
What Are Common Findings?
Abnormal patterns may show increased or decreased levels of specific proteins. For example, a spike in one band could suggest a monoclonal protein (seen in multiple myeloma), while a shift in globulin levels might indicate inflammation or immune system disorders.
Reference range
NCBI: pH 7.35-7.45N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein Electrophoresis (Serum)
Frequently asked questions
What does a protein electrophoresis test show?
How long does it take to get results from this test?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy