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Serum Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood serum using electrophoresis, a technique that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like infections, autoimmune diseases, or protein disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9745-1
Short code
Gamma glob Ur Elph-mCnc
Synonyms
Gamma glob Ur Elph-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates proteins into bands based on their electrical charge and molecular weight. This helps distinguish between normal and abnormal protein profiles, such as albumin, globulins, and other fractions.

Why It’s Done

Your healthcare provider may order this test to diagnose or monitor conditions like multiple myeloma, lymphoma, chronic infections, or kidney disease, where protein levels or patterns may be altered.

Sample Preparation

A blood sample is drawn, and the serum (liquid part after clotting) is prepared for testing. No special preparation is needed, but fasting may be advised depending on clinical context.

Common Conditions Monitored

Abnormal results may indicate conditions affecting protein synthesis, storage, or breakdown, such as liver disease, immune disorders, or genetic protein disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test provides a qualitative overview of protein distribution, which can help pinpoint specific protein abnormalities that may not be detected by general protein tests alone. It’s particularly useful for identifying conditions like monoclonal gammopathies (e.g., multiple myeloma) or dysproteinemias (abnormal protein conditions).

Short name

Serum Protein Electrophoresis

Frequently asked questions

What does a normal result mean?
A normal result suggests balanced protein levels with typical band patterns, though individual variations can occur. However, a single normal test does not rule out underlying conditions requiring further evaluation.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times and clinical urgency.
Can I eat or drink before this test?
No special diet is required, but always follow your healthcare provider’s instructions. If fasting is advised for another reason, follow that instead.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy