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Vitamin E (alpha-tocopherol) concentration in serum/plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate deficiencies or underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
74901-0
Short code
Gamma tocopherol EntSub RBC
Synonyms
Gamma tocopherol EntSub RBC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of vitamin E deficiency, such as nerve problems, muscle weakness, or skin issues. It may also be used to monitor vitamin E levels in people with certain medical conditions, like cystic fibrosis or malabsorption disorders, or those taking supplements.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the blood draw, but this depends on your provider’s instructions. Bring any medications or supplements you’re taking to your appointment.

During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample will be sent to a lab for analysis.

What the Results Mean

Results are typically reported as a concentration of vitamin E in the blood. While reference ranges vary by lab, low levels may suggest deficiency, while very high levels could indicate over-supplementation or certain medical conditions.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low vitamin E levels can lead to oxidative stress, affecting nerve function, vision, and immune response. Deficiency is rare but may occur in people with poor absorption (e.g., celiac disease, pancreatitis) or chronic liver disease. High levels may raise concerns if they’re due to excessive supplementation or rare genetic disorders.

Short name

Vitamin E Level

Frequently asked questions

How long does it take to get my results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they’re ready to discuss the findings.
Can I take vitamin E supplements before the test?
Yes, but inform your provider about any supplements or medications you’re taking, including vitamin E. They may advise adjusting timing or dosage to avoid interference with test accuracy.
What symptoms might indicate vitamin E deficiency?
Symptoms can include nerve damage (tingling, weakness), vision problems, muscle coordination issues, or skin changes. If you experience these symptoms, discuss them with your doctor, as vitamin E deficiency is often asymptomatic until it’s severe.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy