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Vitamin E (Alpha-Tocopherol) Serum Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood serum. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports immune function and may help prevent certain health issues linked to oxidative stress."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
63370-1
Short code
Gamma tocopherol SerPl-mCnc
Synonyms
Gamma tocopherol SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
5
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms of vitamin E deficiency, such as muscle weakness, nerve problems, or vision issues. It may also be checked in people with certain genetic disorders, malabsorption problems (like celiac disease or Crohn’s), or those taking certain medications that can affect vitamin E levels.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your lab requires it, but always follow your provider’s instructions. Bring any medications you’re taking to your appointment.

How the Test Is Done

A blood sample is drawn from a vein in your arm by a healthcare professional. The blood is processed to separate serum, which is then tested for vitamin E levels using a specialized laboratory method.

What the Results Mean

Results are compared to a reference range, but exact values can vary by lab. Low levels may indicate deficiency, while high levels could suggest certain conditions or medications. Your provider will discuss your results in the context of your overall health.

Reference range

NCBI: Vitamin E 5-20 µg/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin E deficiency is rare but can lead to neurological issues, muscle problems, or weakened immune function. It’s often linked to conditions that impair fat absorption (like pancreatitis or cystic fibrosis) or long-term use of certain medications. Early detection helps manage symptoms and prevent complications.

Short name

Vitamin E Level

Frequently asked questions

What causes low vitamin E levels?
Low vitamin E levels may result from poor diet (low intake of vitamin E-rich foods like nuts, seeds, and leafy greens), malabsorption disorders, or certain medications that interfere with its absorption.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they’re ready to review them with you.
Can I eat or drink anything before the test?
Follow your provider’s instructions—some tests require fasting, while others allow light snacks or water. Always confirm with them before the appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy