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Serum Electrolyte Panel with Sodium, Potassium, Chloride, Bicarbonate, and Calcium

Published: August 9, 2026Updated: August 16, 2026

This blood test measures key minerals and chemical balance components in your serum to check how well your body is maintaining fluid and electrolyte levels.

Quick summary

["Essential for detecting imbalances that may affect heart health, muscle function, and overall hydration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93685-6
Short code
Gas + CO + Electrolytes Pnl BldA
Synonyms
Gas + CO + Electrolytes Pnl BldA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Your blood sample is analyzed for five critical electrolytes and related compounds: sodium (Na⁺), potassium (K⁺), chloride (Cl⁻), bicarbonate (HCO₃⁻), and calcium (Ca²⁺). These substances help regulate fluid balance, nerve function, muscle contractions, and bone health.

Why It Matters in Your Body

Electrolytes like sodium and potassium work together to maintain proper fluid distribution, nerve signaling, and muscle function. Bicarbonate helps regulate blood acidity, while calcium supports bone strength and muscle activity. Imbalances can lead to symptoms like fatigue, irregular heartbeat, or muscle cramps.

Common Reasons for Testing

Your doctor may order this test if you have symptoms like excessive thirst, swelling, muscle weakness, confusion, or frequent urination. It’s also used to monitor conditions like heart disease, kidney problems, or metabolic disorders.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm, typically in the morning on an empty stomach. The sample is processed to separate serum (the liquid part) for testing. No special preparation is needed beyond avoiding alcohol or certain medications for 24 hours before testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Electrolyte Panel

Frequently asked questions

Why might my results be different from what’s expected?
Several factors can influence your electrolyte levels, including diet (e.g., high salt intake), dehydration, kidney function, or certain medications. Chronic conditions like diabetes, heart failure, or kidney disease can also affect these measurements. Always discuss any changes in your results with your healthcare provider.
What do low or high levels of these electrolytes usually indicate?
Low sodium (hyponatremia) or high potassium (hyperkalemia) can signal dehydration, kidney issues, or heart problems. Low calcium (hypocalcemia) may relate to bone health concerns, while high bicarbonate (metabolic alkalosis) or low bicarbonate (metabolic acidosis) can indicate acid-base imbalances from conditions like diabetes or kidney disease.
How often should I get this test?
Frequency depends on your health status. Healthy adults may not need routine testing unless advised by a doctor. Those with chronic conditions (e.g., kidney disease, heart failure) may need regular monitoring to track changes in electrolyte levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy