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Serum/plasma mass concentration of Gastrin (fasting)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of gastrin, a hormone produced by cells in the stomach lining, to help diagnose conditions affecting stomach acid production or Zollinger-Ellison syndrome.

Quick summary

["Fasting gastrin levels help identify rare but serious stomach disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51974-4
Short code
Gas Pnl BldCoA
Synonyms
Gas Pnl BldCoA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a fasting gastrin test if you have symptoms like persistent stomach pain, diarrhea, or unexplained ulcers. It’s also used to check for Zollinger-Ellison syndrome, a rare tumor that causes high stomach acid levels, or other conditions like gastroparesis or hyperparathyroidism that may affect hormone balance.

What to Expect Before the Test

You’ll need to fast (no food or drink except water) for 8–12 hours before the test. Avoid smoking and caffeine. Bring any medications to discuss with your provider, as some may affect results.

How the Test Works

A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it’s analyzed for gastrin levels using a specialized immunoassay method to detect hormone concentrations.

What the Results Mean

Results are compared to a reference range for your age and health status. Elevated levels may suggest conditions like Zollinger-Ellison syndrome, while lower levels could indicate stomach issues or other hormonal imbalances. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fasting Gastrin Level

Frequently asked questions

What could cause abnormal results?
High fasting gastrin levels may indicate Zollinger-Ellison syndrome, a tumor producing excess gastrin, or other rare conditions like multiple endocrine neoplasia type 1. Other causes may include stomach ulcers, kidney disease, or certain medications. Low levels could signal conditions like gastroparesis or chronic gastritis.
How might my doctor use these results?
Your doctor may use fasting gastrin levels to guide treatment for stomach ulcers, diagnose Zollinger-Ellison syndrome, or monitor conditions affecting hormone regulation. Follow-up tests or imaging may be needed if abnormalities are detected.
Do I need to prepare differently if I’m pregnant or have a chronic condition?
Yes, inform your doctor about any pregnancy, chronic illnesses (like diabetes or kidney disease), or medications you’re taking. Your preparation instructions may be adjusted based on your health status to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy