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Glucose in Serum (24-Hour Urine Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how well your body is managing glucose levels, which is important for conditions like diabetes.

Quick summary

["Helps diagnose or monitor diabetes and kidney function related to sugar metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110831-5
Short code
GBM IgG Msmt Ser
Synonyms
GBM IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms of diabetes, such as frequent urination, excessive thirst, or unexplained weight changes. It may also be used to check how well your kidneys are filtering glucose from your blood, especially in people with diabetes or other kidney-related conditions.

How the Test Works

You’ll collect all urine produced in a 24-hour period in a special container. The urine is then sent to the lab for analysis to determine the total glucose content.

Sample Collection Process

To prepare, empty your bladder completely at the start of the collection period (typically midnight to midnight). Use a clean container, and discard the first urine sample. Collect all urine for the next 24 hours, including any overnight samples. Store the urine in a cool place until you return it to your healthcare provider.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could affect glucose levels. Follow any specific instructions your doctor provides to ensure accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Glucose

Frequently asked questions

How is this test different from a regular urine glucose test?
A regular urine glucose test checks for glucose in a single sample, while this 24-hour urine test provides a comprehensive picture of your body’s overall glucose excretion over a full day, which can give a clearer picture of long-term glucose control.
Can diet or medications affect this test?
Yes, certain foods, medications (like some diabetes drugs), or even stress can influence glucose levels. Your doctor may recommend avoiding specific foods or medications for a few days before the test to get the most accurate results.
What happens if my urine glucose levels are high?
High urine glucose levels often signal diabetes or kidney problems. Your doctor will discuss next steps, which may include adjusting medications, lifestyle changes, or further testing to understand and manage the underlying cause.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy