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Serum/Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A key measure of kidney function and filtering efficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50767-3
Short code
GD1a Gangl IgG/IgM Ser IA-Rto
Synonyms
GD1a Gangl IgG/IgM Ser IA-Rto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys normally filter waste products, including creatinine, from your blood. High levels of creatinine can signal poor kidney function, while low levels might indicate overhydration or other conditions. This test helps doctors monitor kidney health, especially if you have conditions like diabetes, high blood pressure, or a history of kidney disease.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood. Stay hydrated unless instructed otherwise. Avoid strenuous activity or medications that may affect kidney function before the test.

Common Causes of Abnormal Results

High creatinine levels may indicate reduced kidney function, dehydration, or conditions like heart failure or severe muscle breakdown. Low levels could suggest overhydration, low muscle mass, or certain medications. Always discuss results with your healthcare provider.

How This Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. The blood sample is sent to a lab for analysis. The test typically takes a few minutes, and you may feel slight discomfort but no lasting effects.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

What does a high creatinine level mean?
A high creatinine level often signals impaired kidney function, though it can also be influenced by factors like muscle mass, dehydration, or certain medications. Your doctor will consider your overall health and other test results to interpret the meaning.
How often should I get this test?
Your doctor will determine how often you need this test based on your medical history, symptoms, and kidney health. Regular monitoring may be recommended if you have chronic conditions like diabetes or high blood pressure.
Can diet affect creatinine levels?
Dietary protein intake can influence creatinine levels, as muscle metabolism produces this waste product. However, your doctor will assess your results in the context of your overall health, not just diet alone.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy