Ganglioside GM1 (Quantitative) in Serum/Plasma by Line Blot Immunoassay
This test measures the amount of GM1 ganglioside, a complex sugar molecule found in your blood, using a specialized line blot immunoassay method. GM1 is involved in cell signaling and nerve function.
["Assessing GM1 levels may help diagnose or monitor certain neurological conditions."]
Key facts at a glance
- LOINC
- 82395-5
- Short code
- GD1a Gangl IgG Ser Ql Line blot
- Synonyms
- GD1a Gangl IgG Ser Ql Line blot
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- line-blot
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or a history suggestive of conditions affecting nerve cells, such as certain inherited disorders or rare metabolic diseases. It could also be part of a broader evaluation for suspected ganglioside-related pathologies.
What to Expect Before the Test
No special preparation is typically required. You may have blood drawn from a vein in your arm, similar to other blood tests. If you’re on blood-thinning medication, let your provider know before the test.
What the Results Mean
Results are qualitative (present/absent) rather than numerical, as the line blot method detects the presence or relative concentration of GM1. Your provider will interpret the result in the context of your symptoms and medical history.
Common Conditions Monitored
This test is often used to diagnose or confirm conditions like GM1 gangliosidosis, a rare genetic disorder affecting nerve cells, or to investigate unexplained neurological symptoms in patients with suspected ganglioside abnormalities.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated or detectable GM1 in serum/plasma may indicate an underlying metabolic or genetic disorder affecting nerve function. While GM1 is normally present in trace amounts, abnormal levels can signal conditions requiring further investigation, such as lysosomal storage diseases or neurodegenerative disorders. Always consult your provider for accurate interpretation.
Short name
GM1 Ganglioside Test
Frequently asked questions
What does a positive result mean?
Unlike standard blood tests that measure enzyme levels or proteins, this test specifically targets GM1 ganglioside using a line blot immunoassay. It’s designed to detect this particular molecule in serum/plasma, often used for rare neurological disorders.
How long will it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy