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Ganglioside GM1 (Mass Concentration) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specific type of fat molecule, called ganglioside GM1, found in your blood. It may be used to assess certain genetic or metabolic conditions.

Quick summary

["This test helps evaluate rare genetic disorders linked to GM1 storage diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31399-9
Short code
GD1a Gangl IgM Ser-aCnc
Synonyms
GD1a Gangl IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like developmental delays, muscle weakness, or neurological issues. It could also be part of genetic testing for conditions like Gaucher disease or certain lysosomal storage disorders.

What Does the Test Involve?

A blood sample is taken from a vein in your arm. The blood is then processed to measure the concentration of GM1 ganglioside in your serum or plasma.

Sample Preparation and Testing Process

The test uses a specialized laboratory method to detect and quantify GM1 ganglioside. Results are reported as a mass concentration value, which helps determine the presence or severity of potential metabolic disorders.

What Are Possible Results?

Results are interpreted by a healthcare professional based on your clinical picture and may not have a single standard reference range due to the rarity of these conditions. Elevated levels may suggest certain genetic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

GM1 Ganglioside

Frequently asked questions

What does an elevated GM1 ganglioside level mean?
An elevated level may suggest a genetic disorder related to GM1 storage, such as GM1 gangliosidosis. This requires further evaluation by a genetic counselor or specialist to determine the best course of action.
How is this test different from other lipid tests?
Unlike general lipid tests (like cholesterol), this test specifically measures GM1 ganglioside, a unique fat molecule linked to specific metabolic disorders. It’s not a routine screening test but is used in specialized genetic testing contexts.
Do I need to prepare for this test?
No special preparation is needed. However, inform your healthcare provider about any medications or conditions that could affect results, such as certain genetic disorders or metabolic conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy