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Ganglioside GD2 in Serum by Line Blot Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of GD2, a type of ganglioside, in your blood. GD2 is sometimes elevated in certain cancers, including certain types of neuroblastoma or other pediatric malignancies.

Quick summary

["This screening helps doctors monitor for rare blood-related conditions or cancer-related markers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82401-1
Short code
GD2 Gangl IgM Ser Ql Line blot
Synonyms
GD2 Gangl IgM Ser Ql Line blot
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
line-blot
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or risk factors for conditions linked to abnormal GD2 levels, such as certain cancers or metabolic disorders. It may also be part of a broader diagnostic workup for unexplained neurological symptoms or suspected malignancies.

What Does a Positive Result Mean?

A positive result indicates the presence of GD2 in your serum. While elevated levels can be associated with specific cancers or other conditions, further testing and evaluation by a medical professional are needed to determine the cause and next steps.

What Should You Expect During the Test?

This test involves drawing blood from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The blood sample is then analyzed using a line blot immunoassay to detect GD2.

How Is This Test Different from Other Tests?

Unlike standard blood tests that measure common biomarkers like glucose or cholesterol, this test specifically targets GD2, a less commonly measured ganglioside. It’s typically used in specialized clinical settings for suspected rare conditions or cancers.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: GD2 in Cancer and Other Conditions

Short name

GD2 Ganglioside Serum Screening

Frequently asked questions

What Are the Common Causes of Abnormal GD2 Levels?
Abnormal GD2 levels can be linked to conditions such as certain cancers (e.g., neuroblastoma), metabolic disorders, or rare genetic conditions. However, GD2 is not typically measured in routine blood tests, so abnormal results often require additional testing and medical evaluation.
How Often Is This Test Performed?
This test is not a routine screening test for the general population. It is usually ordered based on specific clinical indications, such as symptoms, risk factors, or as part of a diagnostic workup for suspected conditions.
Can Diet or Lifestyle Affect GD2 Levels?
There is limited information on how diet or lifestyle factors specifically influence GD2 levels. Since GD2 is a complex molecule often associated with cell membranes and certain cancers, changes in diet or lifestyle may not directly impact GD2 levels unless they influence underlying conditions that could affect it.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy