GDF15 (Growth Differentiation Factor 15) [Mass/Volume] in Serum or Plasma by Immunoassay
GDF15 is a protein released by cells under stress, and this blood test measures its concentration in serum or plasma using an immunoassay method. It is used mainly as a research and clinical aid to assess certain conditions.
["This test measures the level of GDF15, a stress-response protein, in your blood."]
Key facts at a glance
- LOINC
- 92665-9
- Short code
- GDF-15 SerPl IA-mCnc
- Synonyms
- GDF-15 SerPl IA-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Being Measured
GDF15 (growth differentiation factor 15) is a protein that many types of cells produce when they are under stress, injured, or not getting enough oxygen or nutrients. It is sometimes found in higher amounts in the blood in various medical conditions, so doctors and researchers use this test to measure its level.
How the Test Works
A blood sample is collected from a vein in your arm and sent to a laboratory. In the lab, a specific immunoassay method is used to detect and measure the amount of GDF15 present in the serum or plasma portion of your blood. The result is usually reported as a concentration.
What to Expect
Collecting the blood sample is quick and similar to any routine blood draw. You may feel a brief pinch when the needle goes in, and a small bandage is placed afterward. For many blood tests, fasting or other preparation may be requested, so follow any instructions your healthcare provider gives you.
Results and What They Mean
Your result is compared with a reference range that the performing laboratory provides, because ranges can differ between labs and methods. GDF15 levels can rise in many situations, so a single result is generally interpreted alongside your symptoms, medical history, and other test results rather than on its own.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
GDF15 is a biomarker that can be elevated in a wide range of conditions, including metabolic, cardiovascular, inflammatory, and other disorders, and it is used largely as a supportive or research tool. Because it is not specific to any one disease, its clinical significance depends on being interpreted together with other findings by a healthcare professional.
Short name
GDF15
Frequently asked questions
Does an abnormal GDF15 result mean I have a specific disease?
Do I need to fast before this test?
Is GDF15 a routine test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy