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: Genistein [Mass concentration] in Serum or Plasma

Published: August 9, 2026Updated: August 17, 2026

: This test measures the amount of genistein, a soy-derived isoflavone, in a sample of serum or plasma. It is generally used in research or nutritional assessment rather than routine clinical care.

Quick summary

[": Genistein is a plant compound (isoflavone) found mainly in soy; this test measures its concentration in blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
23743-8
Short code
Genistein SerPl-aCnc
Synonyms
Genistein SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Genistein?

: Genistein is a naturally occurring isoflavone, a type of plant compound classified as a phytoestrogen because it can weakly interact with estrogen receptors in the body. It is found in foods such as soybeans, tofu, and other soy products, and is also available as a dietary supplement.

: Why Measure Genistein?

: Measuring genistein in serum or plasma is typically done to assess dietary intake of soy isoflavones, to study how the body absorbs and metabolizes these compounds, or as part of nutritional and research investigations. It is not a standard test for diagnosing disease.

: How the Test Is Done

: A blood sample is collected from a vein, usually in your arm, and the serum or plasma is separated for analysis. The concentration of genistein is then measured using laboratory techniques such as chromatography, sometimes combined with mass spectrometry for accuracy.

: What the Results May Mean

: Results reflect how much genistein is present in your blood at the time of collection, which can be influenced by recent soy intake, supplement use, and individual differences in metabolism. Because there are no broadly established clinical decision thresholds, results are best interpreted by your healthcare provider in the context of your diet and reason for testing.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: Genistein, Serum/Plasma

Frequently asked questions

: Do I need to fast or change my diet before this test?
: Follow any instructions given by your healthcare provider or the laboratory. Because genistein comes from food and supplements, recent soy intake can affect the result, so your provider may ask about your diet or timing of collection.
: Is genistein testing used to diagnose any condition?
: No, it is not a standard diagnostic test. It is generally used for nutritional assessment and research into soy isoflavone intake and metabolism.
: Can supplements affect my genistein level?
: Yes. Soy isoflavone supplements and soy-rich foods can raise blood genistein levels, so tell your provider about any supplements or recent dietary changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy