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Gentamicin trough concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the antibiotic gentamicin in your blood at a specific time, often taken just before the next dose. It helps doctors determine if the drug is working effectively and whether you need adjustments to avoid harmful side effects.

Quick summary

["This test helps ensure your antibiotic dose is safe and effective."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3665-7
Short code
Gentamicin Trough SerPl-mCnc
Synonyms
Gentamicin Trough SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors order a gentamicin trough test if you’re taking gentamicin (an antibiotic) to treat serious infections, such as those caused by bacteria like *Pseudomonas* or *Staphylococcus*. It helps monitor how much of the drug stays in your bloodstream to prevent toxicity while ensuring the infection is treated properly.

What Does the Test Involve?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where the gentamicin level is measured. The test focuses on the lowest point of the drug’s concentration in your blood, known as the ‘trough’ level, to assess its effectiveness.

What Are Common Uses?

This test is most commonly used in hospitalized patients receiving intravenous gentamicin, especially those with kidney issues or infections requiring high doses. It helps adjust the dose to avoid over-exposure, which can damage kidneys or nerves.

How Often Is This Test Done?

The frequency depends on your treatment plan. Typically, it’s done once or twice weekly to check levels, especially if you’re receiving high doses or have kidney problems. Your doctor will decide based on your medical needs.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Gentamicin Level (Trough)

Frequently asked questions

Why might my doctor ask for this test?
To ensure your gentamicin dose is safe and effective. High levels can cause kidney damage or nerve problems, while low levels may mean the infection isn’t being treated properly. This test helps balance the risk of side effects with the need to fight infection.
How long will I need to wait for results?
Results are usually available within 1–2 days, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
What if my results are outside the expected range?
If your results are too high, your doctor may reduce your dose or switch to a different antibiotic. If too low, they might increase your dose or extend treatment time to ensure the infection is fully treated.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy