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Glomerular Filtration Rate (GFR) calculated from serum creatinine and other variables

Published: August 9, 2026Updated: August 16, 2026

This test estimates how well your kidneys are filtering waste products from your blood using a formula that includes your serum creatinine level and other factors.

Quick summary

["Your kidneys’ ability to remove waste is a key health indicator—this test helps monitor kidney function over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48643-1
Short code
GFR SerPlBld Creatinine-bsd fmla /1.73sq
Synonyms
GFR SerPlBld Creatinine-bsd fmla /1.73sq
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.6
Ref high
1.3
Critical range
— – 10 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
creatinine-based-formula-mdrd-sq-m-among-black-population
CPT
82565
SNOMED
247997009
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

GFR measures the rate at which blood is filtered by your kidneys. While creatinine is one part of the calculation, the result reflects overall kidney function rather than just creatinine levels alone.

Why Is This Test Done?

Doctors use GFR to check for early kidney problems, track kidney disease progression, or assess kidney function before certain treatments. It’s also useful for managing conditions like diabetes or high blood pressure.

How Is This Test Performed?

A blood sample is taken from a vein (usually in your arm). The lab measures your serum creatinine level and applies a formula (often the CKD-EPI equation) to estimate GFR based on your age, gender, race, and creatinine result.

What Are Common Causes of Abnormal Results?

Low GFR may signal kidney damage, dehydration, heart failure, or other conditions affecting blood flow to the kidneys. High GFR (rarely seen in healthy adults) could indicate overhydration or other metabolic factors.

Reference range

Adult male: 0.7-1.3 mg/dL; Female: 0.6-1.1 mg/dLN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A low GFR is critical because it signals impaired kidney function, increasing risks for waste buildup, fluid imbalance, or related complications like anemia or bone disease. Regular monitoring helps prevent progression of kidney disease.

Short name

GFR (Serum Creatinine-Based)

Frequently asked questions

What does a low GFR mean for my long-term health?
A low GFR means your kidneys may not be working as well as they should, which can raise risks for health problems like high blood pressure, heart disease, or even kidney failure over time. Your doctor may recommend lifestyle changes or closer monitoring.
How often should I expect to have this test?
Your doctor will determine how often you need this test based on your medical history, current health, and any conditions affecting your kidneys. It may be part of routine check-ups or follow-up care for kidney-related issues.
Can diet or medications affect my GFR results?
Yes, certain foods (like high-protein diets), medications (such as NSAIDs or certain antibiotics), or even dehydration can temporarily influence creatinine levels and thus GFR. Always discuss your diet and medications with your doctor before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy