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Glomerular Filtration Rate (GFR) calculated from serum creatinine concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter waste products from your blood, using your serum creatinine level. It helps assess kidney function and identify early kidney damage.

Quick summary

["Your GFR helps doctors track kidney health and guide treatment for conditions like diabetes or high blood pressure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62238-1
Short code
GFR SerPlBld Creatinine-bsd fmla CKD-EPI
Synonyms
GFR SerPlBld Creatinine-bsd fmla CKD-EPI
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.6
Ref high
1.3
Critical range
— – 10 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
creatinine-based-formula-ckd-epi-sq-m
CPT
82565
SNOMED
247997009
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Your Kidneys Matter

Kidneys filter waste and extra fluids from your blood, balancing important chemicals like creatinine. When kidneys don’t work well, waste builds up, which can harm your body. This test helps check how effectively your kidneys are doing this job.

How the Test Works

Your doctor uses a formula that includes your serum creatinine level (from a blood draw) and other factors like age, sex, and body size to estimate your GFR. Creatinine is a waste product from muscle breakdown that kidneys normally remove.

What to Expect Before the Test

You’ll have a simple blood draw, usually at your doctor’s office or lab. No special preparation is needed, but tell your doctor about any medications or recent illnesses that might affect results.

Possible Results and Next Steps

Your GFR result helps determine if your kidneys are working as they should. Very low GFR may signal kidney problems, while normal levels suggest healthy filtering. Your doctor will discuss results with you and may recommend follow-up tests or adjustments to your treatment plan.

Reference range

Adult male: 0.7-1.3 mg/dL; Female: 0.6-1.1 mg/dLN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A low GFR often indicates kidney disease, which can lead to serious health risks like fluid buildup, high blood pressure, or even heart problems. Early detection allows for timely treatment to slow progression. High GFR may sometimes suggest kidney overfunctioning or conditions like polycystic kidney disease, but this is less common and requires further evaluation.

Short name

GFR (Creatinine-Based)

Frequently asked questions

What causes a GFR test to be done?
Your doctor may order this test if you have symptoms like fatigue, swelling, frequent urination, or if you have conditions like diabetes, high blood pressure, or a family history of kidney disease. It’s also part of routine check-ups for people at higher risk.
How often should I get this test?
Frequency depends on your health. Healthy adults may get it once every few years. People with chronic conditions like diabetes or kidney disease may need it more often, as recommended by their doctor.
Can diet or medications affect my GFR?
Yes. High-protein diets or certain medications (like NSAIDs like ibuprofen) can temporarily raise creatinine levels. Always tell your doctor about all medications, supplements, or dietary changes before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy