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Calculated Glomerular Filtration Rate (GFR) from Serum Creatinine and Other Parameters

Published: August 9, 2026Updated: August 16, 2026

This test estimates how well your kidneys are filtering waste products from your blood, using a formula that includes your serum creatinine level and other blood measurements.

Quick summary

["Your kidneys’ filtering ability helps determine kidney function and risk for kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50044-7
Short code
GFR SerPlBld Creatinine-bsd fmla FML
Synonyms
GFR SerPlBld Creatinine-bsd fmla FML
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.6
Ref high
1.3
Critical range
— – 10 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
creatinine-based-formula-mdrd-sq-m-among-female-population
CPT
82565
SNOMED
247997009
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Kidney Health

GFR measures how efficiently your kidneys remove waste and excess fluids from your blood. While creatinine alone can give a rough estimate, combining it with other factors helps provide a more accurate picture of kidney function.

How the Test Works

The test uses a mathematical formula (often called the CKD-EPI equation) to calculate GFR from your serum creatinine level and other blood test results, such as age, race, and sometimes blood urea nitrogen (BUN). This helps doctors assess kidney function more precisely than creatinine alone.

When You Might Need This Test

Doctors may order this test if you have symptoms like swelling, frequent urination, fatigue, or if you have risk factors like high blood pressure, diabetes, or a family history of kidney disease. It’s also used to monitor kidney function in people with chronic conditions.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a blood sample drawn, usually from your arm, similar to other blood tests. The sample is sent to a lab for analysis.

Reference range

Adult male: 0.7-1.3 mg/dL; Female: 0.6-1.1 mg/dLN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

GFR (Serum Creatinine-Based)

Frequently asked questions

GFR helps doctors diagnose and monitor kidney disease. Low GFR levels may indicate impaired kidney function, while high levels might suggest overhydration or other conditions. Early detection allows for timely interventions to protect kidney health.
What does a low GFR mean? It may signal kidney problems, such as chronic kidney disease (CKD), and could require lifestyle changes or medical treatment to slow progression.
How often should I get this test? Your doctor will determine frequency based on your health, symptoms, and risk factors—typically every few months or years if you have kidney concerns.
Can diet affect my GFR? Yes, high sodium, protein, or fluid intake can impact kidney function, so your doctor may recommend dietary adjustments if needed.
Is this test painful? Blood draws are generally mild discomfort, but most people tolerate it well. You may feel a slight pinch or sting during the procedure.
What if my results are abnormal? Your doctor will discuss them with you, including next steps like further testing, lifestyle changes, or treatment options tailored to your needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy