24-Hour Urinary Gamma-Glutamyl Transferase (GGT) Activity Rate
This test measures how much of an enzyme called gamma-glutamyl transferase (GGT) is excreted in your urine over a full day. GGT is involved in breaking down certain amino acids, and its presence in urine may indicate liver or bile duct health.
["GGT in urine can help assess liver function or potential bile duct issues over a 24-hour period."]
Key facts at a glance
- LOINC
- 58768-3
- Short code
- GGT 24h Ur-cRate
- Synonyms
- GGT 24h Ur-cRate
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 8
- Ref high
- 61
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82977
- SNOMED
- 3110003
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like jaundice (yellowing of skin/eyes), unexplained fatigue, abdominal pain, or if they suspect liver disease, bile duct blockage, or other conditions affecting metabolism. It can also be part of routine monitoring for chronic liver conditions.
What to Expect Before the Test
No special preparation is needed. You’ll collect all urine produced in a 24-hour period in a sterile container, starting and ending with your first morning urine. Label each collection properly and return it to your lab within the specified timeframe.
How the Test Works
The lab analyzes the urine sample to measure the enzyme activity rate. This involves detecting GGT levels that reflect how much of the enzyme was excreted during the day, often using enzymatic methods to quantify activity.
What the Results Mean
Results are compared to a general reference range for healthy individuals, though values can vary based on age, sex, and health status. Elevated levels may suggest liver or bile duct problems, while normal levels do not rule out all conditions.
Reference range
Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
24h Urine GGT Rate
Frequently asked questions
What does elevated GGT in urine typically indicate?
Can diet or medications affect this test?
How often should this test be repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy