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Glucose in Serum (24-Hour Urine Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) excreted in your urine over a 24-hour period. It helps assess how well your body is managing glucose levels, especially if you have diabetes or other conditions affecting sugar metabolism.

Quick summary

["This test helps track how your body handles sugar over time and may indicate diabetes or other metabolic issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96593-9
Short code
GGT DBS-cCnc
Synonyms
GGT DBS-cCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a 24-hour urine glucose test if they suspect diabetes, prediabetes, or other conditions like kidney disease, gestational diabetes, or unexplained weight changes. It can also be used to monitor long-term glucose control in people with diabetes.

How the Test Works

You’ll collect all urine for a full 24-hour period in a special container. The test measures the total glucose lost in your urine, which reflects how much sugar your body isn’t reabsorbing back into your bloodstream.

Sample Collection

You’ll start by emptying your bladder into the container at the beginning of the 24-hour period (e.g., midnight). After that, you’ll collect every drop of urine for the next 24 hours, including during sleep. Store the sample in a cool place until you return it to the lab.

What to Expect

No special preparation is needed, but avoid taking diuretics (like caffeine or some medications) that could affect urine volume. Drink fluids normally unless instructed otherwise.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High urine glucose levels may indicate diabetes, where the body struggles to regulate blood sugar. It can also signal kidney issues or other metabolic disorders. Low levels might suggest the body is absorbing glucose efficiently, but this is less common in routine testing.

Short name

24-Hour Urine Glucose

Frequently asked questions

What does a high urine glucose level mean?
A high result often means your body isn’t effectively controlling blood sugar, which could signal diabetes or poor management of existing diabetes. Your doctor may recommend lifestyle changes, medication adjustments, or further testing.
How is this test different from a blood glucose test?
Unlike blood glucose tests (like fasting glucose or HbA1c), this test measures sugar lost in urine over a full day. It provides a broader picture of how much sugar your body is processing and excreting, which can help assess long-term glucose handling.
Can I drink alcohol before this test?
Yes, but avoid excessive alcohol, as it may affect urine volume or glucose metabolism. Stick to your usual fluid intake unless your doctor specifies otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy