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Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function is evaluated by checking creatinine levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49945-9
Short code
GH 10:30 PM SerPl-aCnc
Synonyms
GH 10:30 PM SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for kidney problems, monitor kidney function over time, or evaluate conditions like dehydration, heart disease, or muscle disorders. It’s often used alongside other tests to diagnose or monitor chronic kidney disease.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a larger panel. Drink plenty of water the day before to ensure normal kidney function. Avoid strenuous exercise or certain medications that could affect results.

What Happens During the Test?

A healthcare professional will draw blood from a vein, typically in your arm. The blood sample is sent to a lab for analysis. The test takes a few minutes, but the process may take longer depending on your vein access.

What the Results Mean

Results help determine if your kidneys are working properly. High levels may indicate kidney damage or disease, while very low levels could suggest muscle disorders, severe dehydration, or liver problems. Your doctor will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function because they reflect how well blood is filtered. Elevated levels often signal impaired kidney function, which can lead to complications like fluid buildup, electrolyte imbalances, or even heart disease. Regular monitoring is important for people with chronic kidney disease or risk factors like diabetes or high blood pressure.

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status. People with kidney disease may need it monthly or more frequently, while others with no known issues might get it once a year or less.
Can diet or exercise affect my creatinine levels?
Dietary protein intake can influence creatinine levels, but eating a balanced diet is still important. Exercise generally doesn’t affect creatinine levels directly, but it may impact muscle mass, which could slightly alter results. Always follow your doctor’s advice about diet and activity.
What if my results are abnormal?
If your results are outside the expected range, your doctor will discuss them with you. They may recommend further tests, adjustments to your treatment plan, or lifestyle changes to improve kidney health. Never interpret results alone—always talk to your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy