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Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your plasma. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49947-5
Short code
GH 11:30 PM SerPl-aCnc
Synonyms
GH 11:30 PM SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. High levels can indicate kidney problems, while low levels might suggest dehydration or muscle loss. This test is often used alongside other kidney function tests to monitor overall kidney health.

What to Expect Before the Test

You’ll typically have a small tube inserted into a vein in your arm. Blood will be drawn into a test tube. No special preparation is needed, but inform your doctor about any medications or recent illnesses, as they may affect results.

How the Test Works

Your blood sample is sent to a lab where it is analyzed to measure creatinine levels. The test uses a method called **nephelometry** or **enzymatic assay** to detect and quantify creatinine concentration.

Common Causes of Abnormal Results

Elevated creatinine levels may signal impaired kidney function, dehydration, or conditions like heart failure or muscle disorders. Low levels could indicate dehydration, severe muscle wasting, or liver disease. Always discuss results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

What if my creatinine level is high?
A high creatinine level may suggest your kidneys aren’t working as well as they should. Your doctor might recommend further tests or adjustments to your medications to manage any underlying kidney issues.
Why do I need this test regularly?
Regular creatinine tests are often part of ongoing kidney monitoring, especially if you have conditions like diabetes, high blood pressure, or a history of kidney problems. They help track changes over time and guide treatment decisions.
Can diet affect my creatinine test results?
Yes, high-protein foods or dehydration can temporarily raise creatinine levels. Avoid excessive protein intake 24 hours before the test, and drink plenty of water the day before to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy