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Serum/plasma mass concentration of glucagon

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucagon, a hormone produced by cells in your pancreas, in your blood. Glucagon helps regulate blood sugar levels by signaling your liver to release glucose.

Quick summary

["Glucagon levels can help diagnose or monitor conditions affecting blood sugar or pancreatic function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47749-7
Short code
GH 1.5h p Gc SerPl-aCnc
Synonyms
GH 1.5h p Gc SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a glucagon test if you have symptoms like unusually low blood sugar (hypoglycemia), unexplained weight loss, or signs of pancreatic issues. It may also be used to assess conditions like diabetes, pancreatic tumors, or metabolic disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if instructed by your healthcare provider. Bring any medications you’re taking to your appointment.

How the Test Is Performed

A blood sample is drawn from a vein, typically in your arm, using a small needle. The sample is sent to a lab for analysis to measure glucagon levels.

Possible Results and Interpretation

Results are compared to standard reference ranges, though exact values can vary by lab. High glucagon levels may suggest pancreatic tumors or other endocrine disorders, while low levels could indicate certain metabolic or genetic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal glucagon levels can indicate underlying conditions such as multiple endocrine neoplasia (MEN) syndrome, pancreatic neuroendocrine tumors, or rare metabolic disorders. Your doctor will review results in the context of your symptoms and medical history to guide further testing or treatment.

Short name

Glucagon Level

Frequently asked questions

What causes glucagon levels to be high?
High glucagon levels may be linked to pancreatic tumors (such as glucagonoma), chronic pancreatitis, or certain metabolic disorders. It can also occur in people with diabetes who experience prolonged low blood sugar.
What causes glucagon levels to be low?
Low glucagon levels are less common but may result from genetic disorders affecting hormone production, severe liver disease, or certain medications that interfere with hormone regulation.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during a follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy