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Plasma/Serum Total Protein with Albumin and Globulin Separation (Bromocresol Green Electrophoresis)

Published: August 9, 2026Updated: August 17, 2026

This test measures the different protein components in your blood, including albumin and globulins, using a technique called bromocresol green electrophoresis.

Quick summary

["Understanding your blood protein profile can help identify imbalances that may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
47887-5
Short code
GH 1.5h p Orn SerPl-aCnc
Synonyms
GH 1.5h p Orn SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions like kidney disease, liver problems, infections, or certain cancers. It can also help check for nutritional deficiencies or evaluate how well your body is producing proteins.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw blood. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.

What the Results Mean

The test separates proteins into bands based on size and charge. Albumin appears as a distinct band, while globulins (like alpha, beta, and gamma globulins) appear as other bands. Abnormal patterns may indicate conditions affecting protein production or breakdown.

Common Conditions Monitored

High or low levels of specific proteins can signal issues like chronic kidney disease (reduced albumin), multiple myeloma (elevated monoclonal proteins), or liver disease (altered globulin patterns).

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis

Frequently asked questions

What does a high or low total protein level mean?
A high total protein level may suggest dehydration, chronic inflammation, or certain cancers. A low level could indicate malnutrition, liver or kidney disease, or severe infections. Your doctor will consider your overall health and symptoms to interpret results.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow-up with your healthcare provider to discuss findings.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise. This test doesn’t require fasting, but check with your provider if you have questions about timing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy