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Serum/plasma mass concentration of total protein (by nephelometry)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum or plasma, which helps assess overall protein levels in your body.

Quick summary

["Total protein levels reflect your body’s protein balance and can indicate hydration or liver/kidney health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14142-4
Short code
GH 15M p chal SerPl-mCnc
Synonyms
GH 15M p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like dehydration, liver disease, kidney disease, or malnutrition. It can also help diagnose or monitor certain medical conditions by evaluating your blood’s protein content.

What Does a Low or High Protein Level Mean?

Low protein levels might suggest dehydration, liver problems, or kidney issues, while high levels could indicate dehydration, multiple myeloma, or severe burns. However, results depend on your overall health and medical history.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then separated into serum (liquid after clotting) or plasma (liquid before clotting) for testing. This test does not require fasting.

Common Conditions Monitored

This test is often used alongside other blood tests to diagnose or monitor conditions such as kidney disease, liver disease, malnutrition, or certain cancers. It can also help assess hydration status.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What does a normal range of total protein mean for me?
A normal range is not a single number but a general guideline. Your actual results will be compared to your specific lab reference values, which may vary slightly by lab. Your healthcare provider will interpret your results in the context of your health and symptoms.
How long does it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab and healthcare provider’s workflow. Follow-up with your doctor to discuss findings.
Can I eat or drink before this test?
No special preparation is needed. You can eat and drink normally before the blood draw, as this test does not require fasting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy