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Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood plasma. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
47889-1
Short code
GH 1.75h p Orn SerPl-aCnc
Synonyms
GH 1.75h p Orn SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. High levels can indicate kidney damage or disease, while low levels may suggest dehydration or muscle loss. This test is often used alongside other kidney function tests to monitor overall kidney health.

What to Expect Before the Test

You’ll typically have a small blood sample drawn from a vein in your arm. No special preparation is usually needed, but inform your healthcare provider about any medications or recent illnesses, as they may affect results.

Common Causes of Abnormal Results

Elevated creatinine levels may be due to kidney problems, dehydration, or conditions that reduce blood flow to the kidneys. Low levels can result from dehydration, muscle atrophy, or certain medical conditions. Always discuss any concerns with your doctor.

How the Test Works

Blood is collected and analyzed to measure creatinine concentration using a specialized laboratory method that detects waste products in your plasma.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

How often will I need this test?
Your doctor may order this test periodically to monitor kidney function, especially if you have a history of kidney issues, diabetes, high blood pressure, or other conditions that affect the kidneys. Frequency depends on your health status and treatment plan.
What if my results are out of range?
If your results are abnormal, your doctor will review them with you and may recommend further testing or adjustments to your treatment. They’ll also discuss lifestyle changes or medications that could help improve kidney function if needed.
Can diet or exercise affect this test?
Dietary changes, such as eating more protein, can temporarily affect creatinine levels. Avoiding excessive protein intake for a few days before testing may help stabilize results. Staying hydrated is important, but drinking too much water before the test could dilute the results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy