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Serum or Plasma Creatinine (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of creatinine, a waste product from muscle metabolism that your kidneys filter out of your blood. It helps assess kidney function.

Quick summary

Kidney function check: creatinine levels help doctors monitor how well your kidneys are working.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47928-7
Short code
GH 1h p betaxolol+Gc SerPl-aCnc
Synonyms
GH 1h p betaxolol+Gc SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your doctor may order a creatinine blood test to check how well your kidneys are working. It can help screen for kidney disease, monitor an existing kidney condition, and make sure medicines or treatments are not harming your kidneys. It is often included in a routine metabolic panel or done before imaging scans that use contrast dye.

Your doctor may order this test to check for kidney problems, track kidney disease progression, or evaluate kidney function before certain procedures. It’s also used to monitor long-term conditions like diabetes or heart disease.

The test is a simple blood draw, usually taken from a vein in your arm, and it takes only a few minutes. You may feel a quick sting when the needle goes in. Afterward, a small bandage is placed on the spot, and you can return to your normal activities right away. Results are often ready within a day or two.

A small blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it’s quick. No special preparation is needed unless instructed otherwise.

Creatinine is a waste product your muscles produce as they use energy. Healthy kidneys filter it out of your blood and remove it through your urine. By measuring the amount of creatinine in your blood, and sometimes in a urine sample, your doctor can estimate how well your kidneys are filtering, often reported as an estimated glomerular filtration rate (eGFR).

Creatinine is measured using a standard laboratory method that detects its concentration in your blood or plasma/serum. This helps determine how well your kidneys are removing waste.

Typical blood creatinine ranges are about 0.7 to 1.3 mg/dL for adult men and 0.6 to 1.1 mg/dL for adult women, although exact ranges can vary between labs. Higher levels may point to reduced kidney function, dehydration, or other conditions, while lower levels are less common and may relate to low muscle mass or pregnancy. Your doctor will interpret your result along with your age, sex, and overall health.

Results are compared to a general reference range, but individual ranges can vary by lab. High levels may suggest kidney issues, while low levels could indicate dehydration or muscle loss.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

What does a high creatinine level mean?
What does a low creatinine level mean? A low creatinine level usually is not a cause for alarm. It often reflects lower muscle mass, which can be normal in older adults, or it can occur during pregnancy. In some cases it may be linked to severe muscle loss, liver disease, or poor nutrition, so your doctor will review your full results before deciding if more testing is needed.
Low creatinine levels may suggest dehydration, muscle loss, or conditions that affect muscle breakdown. They can also occur in people with very little muscle mass. Your doctor will consider other factors, like diet or medications, to understand the cause.
How often should I get this test? That depends on your health. If your kidneys are healthy and the test was part of a routine checkup, once a year may be enough. If you have kidney disease, diabetes, high blood pressure, or take medicines that can affect your kidneys, your doctor may recommend testing every few months to keep track of your kidney function.
Your doctor will determine how often you need this test based on your health condition. For example, people with kidney disease may need it more frequently, while others might only need it once or twice a year.
Typically, you can eat and drink normally before this test unless your doctor advises otherwise. Some tests may require fasting, but creatinine tests do not.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy