Total Protein with Albumin/Globulin Ratio (Serum/Plasma)
This test measures your blood’s total protein levels and evaluates the balance between albumin and globulin proteins, which are key to maintaining fluid balance, immune function, and tissue health.
["Helps assess protein metabolism, kidney function, and potential nutritional deficiencies."]
Key facts at a glance
- LOINC
- 47893-3
- Short code
- GH 1h p Gc SerPl-aCnc
- Synonyms
- GH 1h p Gc SerPl-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Total protein combines albumin and globulin proteins found in your blood. Albumin helps regulate fluid distribution in your body, while globulins support immune function and transport certain substances. The ratio between these proteins can indicate underlying health conditions, such as liver disease or kidney problems.
Why Is This Test Done?
Your doctor may order this test to check for conditions like malnutrition, liver disease, kidney disease, or chronic inflammation. It can also help monitor treatment effectiveness for conditions affecting protein production or breakdown.
Common Conditions Monitored
Abnormal results may signal conditions such as protein-losing disorders, liver cirrhosis, or severe infections. High protein levels might suggest dehydration or certain cancers, while low levels could indicate malnutrition or kidney disease.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum (if drawn without an anticoagulant) or plasma (if drawn with an anticoagulant). This sample is then analyzed in a lab using specialized techniques to measure protein components.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Protein profile test
Frequently asked questions
How might my results affect my health?
What can I do to prepare for this test?
Will this test hurt?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy